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The Latest on SIBO/IMO/IBS with Dr. Mark Pimentel (Feb. 14, 2022)

Dr. Pimentel is the top research doctor in the fields of IBS (Irritable Bowel Syndrome), SIBO (Small Intestine Bacterial Overgrowth), IMO (Intestinal Methanogen Overgrowth), and other functional gut disorders. He and his team are working tirelessly in the MAST-Pimentel Laboratory at Cedars-Sinai Medical Center in Los Angeles to find a cure for these gut motility diseases.

Dr. Pimentel is the man we have to thank for...

  • Sequencing the small intestine microbiome
  • Identifying post-infectious IBS (aka IBS caused by past food poisoning) as an underlying cause
  • Creating the blood test to diagnose post-infectious IBS (called IBS Smart)
  • Separating IMO (intestinal methanogen overgrowth) as a "separate" condition from SIBO
  • Pioneering treatments for SIBO, including Rifaximin and the Elemental Diet
  • Creating the Cedars-Sinai low-fermentation diet that has helped thousands of people find relief
  • Creating the first breath test for all 3 gases: methane, hydrogen, and hydrogen sulfide (called Trio Smart)

I could go on, but suffice it to say Dr. Pimentel is a pioneer, and I am extremely honored to have the chance to sit down and interview him again.

(And as a BONUS, Dr. Allison Siebecker joined us LIVE on the call!)



In a recent study, it was determined that hydrogen is consumed to produce methane and hydrogen sulfide. Trio-smart™ provides a complete picture of this complex interplay with measurements of hydrogen, methane and hydrogen sulfide.

Trio-smart™ is the only breath test to measure hydrogen sulfide, which is correlated to diarrhea. Available from Gemelli labs which you can order for yourself by filling out the questionnaire.

In a recent study, subjects with elevated levels of hydrogen sulfide had the greatest diarrhea among subjects referred for testing. Patients with elevated hydrogen sulfide levels may have appeared "normal" on previous breath tests.

Trio-smart™ uses best-in-class breath testing technology.

In a recent study, the device used for trio-smart™ testing was determined to be “at least equivalent to conventional breath testing for assessing bacterial overgrowth.”

The IBS Smart Test. A simple antibody blood test that is making IBS easier to accurately diagnose... and revealing the root cause behind the disorder! (You may have heard of it if you follow Dr. Mark Pimentel's groundbreaking research.)

// About

Dr. Mark Pimentel is the top research doctor in the fields of IBS (Irritable Bowel Syndrome), SIBO (Small Intestine Bacterial Overgrowth), and other functional gut disorders. He spends his days working tirelessly in the Pimentel Laboratory at Cedars-Sinai Medical Center in Los Angeles. 

Shivan Sarna is the author of Healing SIBO, TV host, and the creator of the SIBO SOS® Summits and Community, the Digestion SOS™ documentary series, the Gut & Microbiome Rescue Summit, the Lymphatic Rescue Summit, the Dental-Health Connection Summit, and Chronic Condition Research, a 501(c) 3 non-profit to further research under-funded medical conditions. After a lifetime of struggling with health issues, Shivan made it her mission to demystify her own health struggles - and to share that information with others who were struggling. Her special skill is finding and connecting with the leading expert doctors and connecting those experts with the people who need their help. Her personal mantra is SOS: Save Our Selves, and that's what she has helped thousands of people do! 

Dr. Allison Siebecker is Instructor of Advanced Gastroenterology at NUNM, an award-winning author, and the 2021 lifetime achievement award recipient from the Gastroenterology Association of Naturopathic Physicians. She was the former medical director and co-founder of the SIBO Center for Digestive Health at NUNM. Dr. Siebecker has specialized exclusively in SIBO since 2011, serving as a second and third opinion referral doctor for patients who have failed previous treatments, and is the creator of many staple SIBO treatments. Dr. Siebecker is passionate about education, she has been teaching physicians, medical students and patients internationally since 2010, with many going on to become SIBO specialists and teachers, sharing alongside her at conferences and in their own courses, websites and books.

 Fix the real cause of SIBO, IBS, Bloating...

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